WHiTE 5

Hip fractures are a serious injury, especially in older people, with over 80,000 cases each year in the UK. They can be life-threatening, with around 25% of patients dying within a year and many others losing independence and quality of life. 

The most common treatment for a hip fracture is a partial hip replacement. The partial hip replacement can be attached to the thigh bone with or without bone cement. Surgeons argue about whether or not to use bone cement when fixing the hip replacement to the bone.

The WHiTE 5 study was a randomised controlled trial comparing cemented and uncemented types of hip implants.

External Links

Here are relevant links to the study...

• [Main Study Report] 'Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture' published in New England Journal of Medicine
• [Main Economic Evaluation] 'Cost-utility analysis of cemented hemiarthroplasty versus hydroxyapatite-coated uncemented hemiarthroplasty for the treatment of displaced intracapsular hip fractures: the World Hip Trauma Evaluation 5 (WHiTE 5) trial' published in The Bone and Joint Journal
• [Sub-group Analysis] 'Are there patients with an intracapsular fracture of the hip who may benefit from an uncemented hemiarthroplasty? A causal forest analysis of the WHiTE 5 randomized clinical trial' published in The Bone and Joint Journal